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The results showed that sulfobutyl etherβcyclodextrin could enhance the water solubility and stability of isoliquiritigenin. In parenteral applications, modified cds, such as sulfobutyletherβcyclodextrin sbeβcd and hydroxypropylβcyclodextrin hpβcd, are employed due to their higher aqueous solubility and lower nephrotoxicity 81. The results showed that sulfobutyl etherβcyclodextrin could enhance the water solubility and stability of isoliquiritigenin. In this research the separation of the enantiomers of the basic drug bidisomide sc‒40230 from five closely related known process impurities was investigated using several.

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